Possessing incredible superhuman strength and endurance, telekinesis, a brilliant scientific and strategic mind, and an obsession with the embodiment of Death, the being known as the Mad Titan is one of the most formidable in all comics. Unique among major villains in that he is not the nemesis of any one particular hero. Through his callousness and attempts to impress Lady Death, Thanos has crossed paths with virtually all cosmic heroes, and just about all of the Earth-based ones as well. Never was he more powerful than when he located all six of the Infinity Gems and created the Infinity Gauntlet, granting him control over reality, time, space, power, the mind, and the soul. He was omnipotent, omniscient, and omnipresent…basically the most powerful being to ever exist.
49. Scarlet Witch
The daughter of Magneto and twin sister of fellow mutant hero Quicksilver. As her name would imply, Wanda Maximoff has the ability to cast all sorts of spells and hexes, but what makes her truly powerful is her ability to alter and control reality itself. So incredible is this power that in the “Decimation” story arc, with the utterance of the simple phrase “No more mutants,” Scarlet Witch wiped out about 99% of the world’s mutant population. With her mutant genetics, she has had short stints with some of Marvel’s X-teams, but she is most often portrayed as a long-standing member of The Avengers. Her tenure with Earth’s Mightiest Heroes eventually lead her to a romantic relationship with the android Vision.
The Norse god of mischief, Loki is the adopted son of Odin and brother of Thor. Loki desires for nothing more than power and control. He believes that his brother is a brash, hot-headed, brainless warmonger who is far less fit for the throne of Asgard than he. Because of this the relationship with his adoptive brother is almost always one of contention, though they have worked together one more than one occasion. Loki is also responsible for the creation of The Avengers, as events he set in motion necessitated several of Earth’s heroes banding together to stop them.
47. Captain Marvel (Shazam)
DC Comics’ Captain Marvel, though due to a lawsuit with Marvel Comics, he is otherwise known as Shazam. When the child Billy Batson utters the word “Shazam!” he transforms into an adult with power that rivals that of Superman. He is virtually immortal and invincible, can shoot and control lightning, has a genius-level intellect, can fly, and possesses superhuman strength and speed. While Captain Marvel is typically regarded as a character from a bygone era, he was never more modern or relevant (or dangerous) than he was in Alex Ross and Mark Waid’s masterpiece Kingdom Come, when he is manipulated and controlled by Lex Luthor into a climactic showdown with the Man of Steel…a fight that eventually leads to the death of nearly all of DC’s heroes.
46. Archie Andrews
Another iconic character from a simpler time. The last holdover from the days of wholesome, strictly family-friendly comics. Portrayed as the all-American boy-next-door, Archie Andrews and the comic that shares his name epitomized the look and feel of the 1940’s and 50’s. Unlike most comic characters, whose appearances change slightly depending on the artist, Archie and the rest of the gang from Riverdale have remained mostly the same throughout the vast majority of their 70-plus years of existence. Only in the recent years was a change made to make the characters appear more current. The cartoonish style in which the characters were drawn has become synonymous with the characters themselves, leading people to refer to it as the “Archie-style.” Archie is also notable in that he is the only major comic character to have an entire publication company named after it.